Van Leuven JT, Meister RC, Simon C, McCutcheon JP. 2014. Sympatric speciation in a bacterial endosymbiont results in two genomes with the functionality of one. Cell, in press. [Link to the article at Cell]

[This article was selected for the video abstract for the 11 September 2014 issue of Cell.]

McCutcheon JP and Keeling, PJ. 2014. Endosymbiosis: Protein targeting further erodes the organelle/symbiont distinction. Current Biology 24:R654–R655. [Link to the article at Current Biology]

Duncan RP, Husnik F, Van Leuven JT, Gilbert D, Davalos, L, McCutcheon JP, Wilson ACC. 2014. Dynamic recruitment of amino acid transporters to the insect-symbiont interface. Molecular Ecology 23:1608–1623. [ Link to the article at Molecular Ecology]

[This article was selected for a special issue of the journal, Nature's Microbiome.]


McCutcheon JP. 2013. Genome evolution: a bacterium with a Napoleon complex. Current Biology 23:R657–R659. [Link to the article at Current Biology]

Husnik F, Nikoh N, Koga R, Ross L, Duncan RP, Fujie M, Tanaka M, Satoh N, Bachtrog D, Wilson ACC, von Dohlen CD, Fukatsu T, McCutcheon JP. 2013. Horizontal gene transfer from diverse bacteria to an insect genome enables a tripartite nested mealybug symbiosis. Cell 153:1567–1578. [Link to the article at Cell]

[This article was featured on the cover of Cell, and was highlighted at National Geographic, the New York Times, the LA Times, Scientific American, Quanta Magazine, the Missoulian, Cell Host & Microbe, Nature Reviews Microbiology, and the ASM blog Small Things Considered.]

Brown AMV, Huynh LY, Bolender CM, Nelson KG, McCutcheon JP. 2013. Population genomics of a symbiont in the early stages of a pest invasion. Molecular Ecology. 23:1516–1530 [ Link to the article at Molecular Ecology]

[This article was selected for a special issue of the journal, Nature's Microbiome.]


Leavitt SD, Esslinger TL, Spribille T, Divakar PK, Lumbsch HT. 2012. Multilocus phylogeny of the lichen-forming fungal genus Melanohalea (Parmeliaceae, Ascomycota): Insights on diversity, distributions, and a comparison of species tree and concatenated topologies. Molecular Phylogenetics and Evolution 10.1016/j.ympev.2012.09.013.

Spribille T and Muggia L. 2012. Expanded taxon sampling disentangles evolutionary relationships and reveals a new family in Peltigerales (Lecanoromycetidae, Ascomycota). Fungal Diversity 10.1007/s13225-012-0206-5.

Grube M and Spribille T. 2012. Exploring symbiont management in lichens. Molecular Ecology 21:3098-3099.

Van Leuven JT and McCutcheon JP. 2012. An AT mutational bias in the tiny GC-rich endosymbiont genome of Hodgkinia. Genome Biology and Evolution 4:24-27. [Open access article]

[This article was highlighted at Genome Biology and Evolution.]

McCutcheon JP and Moran NA. 2012. Extreme genome reduction in symbiotic bacteria. Nature Reviews Microbiology 10:13-26. [Link to the article at Nature Reviews Microbiology]

[This article was highlighted at Small Things Considered.]


McCutcheon JP and von Dohlen CD. 2011. An interdependent metabolic patchwork in the nested symbiosis of mealybugs. Current Biology 21:1366-1372. [Link to the article at Current Biology]

[This article was highlited at Science, Nature, Current Biology, Scientific American, Small Things Considered, and io9.]


McCutcheon JP and Moran NA. 2010. Functional convergence in reduced genomes of bacterial symbionts spanning 200 million years of evolution. Genome Biology and Evolution 2:708-718. [Open access article]

Woyke T, Tighe D, Mavromatis K, Clum A, Copeland A, Schackwitz W, Lapidus A, Wu D, McCutcheon JP, McDonald BR, Moran NA, Bristow J, Cheng J. 2010. One bacterial cell, one complete genome. PLoS One 5(4):e10314. [Open access article]

Nikoh N, McCutcheon JP, Kudo T, Miyagishima S, Moran NA, Nakabachi A. 2010. Bacterial genes in the aphid genome: absence of functional gene transfer from Buchnera to its host. PLoS Genetics 6(2):e1000827. [Open access article]

The International Aphid Genomics Consortium. 2010. Genome sequence of the pea aphid Acyrthosiphon pisum. PLoS Biology 8(2):e1000313. [Open access article]

McCutcheon JP. 2010. The bacterial essence of tiny symbiont genomes. Current Opinion in Microbiology 13:73-78. [Pubmed abstract]


McCutcheon JP, McDonald BR, and Moran NA. 2009. Convergent evolution of metabolic roles in bacterial co-symbionts of insects. Proceedings of the National Academy of Sciences USA 106:15394-15399. [Free article]

[This paper was a Faculty of 1000 recommended selection.]

McCutcheon JP, McDonald BR, and Moran NA. 2009. Origin of an alternative genetic code in the extremely small and GC-rich genome of a bacterial symbiont. PLoS Genetics 5(7):e1000565. [Open access article]

[This paper was highlighted in Nature Reviews Microbiology and at the NSF website.]


Moran NA, McCutcheon JP, and Nakabachi A. 2008. Genomics and evolution of heritable bacterial symbionts. Annual Review of Genetics 42:165-190. [Pubmed abstract]


McCutcheon JP and Moran NA. 2007. Parallel genomic evolution and metabolic interdependence in an ancient symbiosis. Proceedings of the National Academy of Sciences USA 104:19392-19397. [Free article]

[This paper was highlighted in the In This Issue section of PNAS.]

pre 2007

Shendure J, Porreca GJ, Reppas NB, Lin X, McCutcheon JP, Rosenbaum AM, Wang MD, Zhang K, Mitra RD, and Church GM. 2005. Accurate multiplex polony sequencing of an evolved bacterial genome. Science 309:1728-1732. [ Article free with registration]

McCutcheon JP and Eddy SR. 2003. Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics. Nucleic Acids Research 31:4119-4128. [ Free article]

Clemons WMJr, Broderson DE, McCutcheon JP, May JL, Carter AP, Morgan-Warren RJ, Wimberly BT, and Ramakrishnan V. 2001. Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: purification, crystallization and structure determination. Journal of Molecular Biology 310:827-843.

Clemons WMJr, Wimberly BT, May JL, McCutcheon JP, Capel MS, and Ramakrishnan V. 1999. Structure of a bacterial 30S ribosomal subunit at 5.5 Angstrom resolution. Nature 400:833-840.

Wimberly BT, Guymon R, McCutcheon JP, White SW, and Ramakrishnan V. 1999. A detailed view of a ribosomal active site: the structure of the L11-RNA complex. Cell 97:491-502.

McCutcheon JP, Agrawal RK, Philips SM, Grassucci RA, Gerchman SE, Clemons WMJr, Ramakrishnan V, and Frank J. 1999. Location of translational initiation factor IF3 on the small ribosomal subunit. Proceedings of the National Academy of Sciences USA 96:4301-4306.

Gamble TR, Yoo S, Vajdos FF, von Schwedler UK, Worthylake DK, Wang H, McCutcheon JP, Sundquist WI, and Hill CP. 1997. Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein. Science 278:849-853.

Felden B, Himeno H, Muto A, McCutcheon JP, Atkins JF, and Gesteland RF. 1997. Probing the structure of the Escherichia coli 10Sa RNA (tmRNA). RNA 3:89-103.